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How might impaired renal function affect the clearance, dosing frequency, and efficacy of GLP-1 receptor agonists, such as semaglutide
More than 15% body weight reduction is clinically relevant, resulting in metabolic health improvements, such as improved glycemia and remission of T2D 36
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However, some people choose to keep taking a GLP-1 RA for the long term in order to help maintain their new healthier weight
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